WebGestalt Web API
Explored by:
HUANG, HUILING,FU, JINGYUAN-(Bioinformatics 201, Winter-2022, UCLA)
Description:
WebGestalt is a gene set enrichment analysis tool which helps users interpret lists of interesting genes or proteins from high-throughput experiment results in various biological contexts. The tool supports three complementary methods for enrichment analysis, including :
- Over-Representation Analysis (ORA)
- Gene Set Enrichment Analysis (GSEA)
- Network Topology-based Analysis (NTA)
Various functional databases and reference gene sets are available, and users can upload their own choice of reference set. WebGestalt can be accessed directly at webgestalt.org, and the user manual of the API is detailed at WebGestalt 2019 Manual.
Use cases:
- Retrieve gene set data files of interest (e.g., retrieve the human gene set files in KEGG database for pathway analysis)
- Retrieve gene set enrichment analysis results (e.g., perform gene set enrichment analysis of a specific list of genes with specified organism, enrichment method, FDR method, enrichment database category, enrichment database name, statistically significant method, significant value, maximum number of genes for a category, ID type of the gene list and reference set)